An Air France plane on its way from Brazil to Paris has gone missing with 228 people on board, the airline said on Monday.
Its last known location was unclear. Brazilian television said the Brazilian air force had started a search mission over the Atlantic Ocean for the plane.
Flight AF 447 has 216 passengers and 12 crew on board. It left Rio de Janeiro on Sunday at 7 p.m. local time and was expected in Paris on Monday at 11:15 a.m. (5:15 a.m. EDT).
"Air France regrets to announce that it is without news from flight AF 447, which was flying on the Rio de Janeiro - Paris Charles de Gaulle route and was scheduled to arrive at 11.15 a.m. today (5:15 a.m. EDT)," an Air France spokesman said.
An Air France-KLM spokeswoman in Amsterdam said there had been no radio contact with the missing plane "for a while."
The plane was an Airbus 330-200, according to the Paris airports authority website.
Air France said relatives of people traveling on board flight AF 447 were being taken care of in a special area of Charles de Gaulle airport.